Ca2+sensitization pathways accessed by cholinergic neurotransmission in the murine gastric fundus
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چکیده
منابع مشابه
Investigation of the interaction between cholinergic and nitrergic neurotransmission in the pig gastric fundus.
1. The interaction between the cholinergic and nitrergic innervation was investigated in circular muscle strips of the pig gastric fundus. 2. In physiological salt solution containing 4 x 10(-6) M guanethidine, electrical field stimulation (EFS; 40 V, 0.5 ms, 0.5-32 Hz, 10 s at 4 min intervals) induced small transient relaxations at 0.5-4 Hz, and large frequency-dependent contractions, sometime...
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Nicotine, which is tobacco alkaloid, still induces interests for researchers because of smokers addiction to nicotine. Nicotine having influence on the neuronal acetylcholine receptors (nAChRs) increases release of most certain neurotransmitters from the nerve endings. Also, nicotine, affecting the mitochondrial respiratory chains, contributes to the formation of reactive oxygen species. In the...
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AIM To investigate whether glucagon-like peptide-2 (GLP-2) influences the neurally-induced responses in gastric strips from mice, since no data are available. METHODS For functional experiments, gastric fundal strips were mounted in organ baths containing Krebs-Henseleit solution. Mechanical responses were recorded via force-displacement transducers, which were coupled to a polygraph for cont...
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It is now clear that many neuronal populations release more than one classical neurotransmitter, yet in most cases the functional role of corelease is unknown. Striatal cholinergic interneurons release both glutamate and acetylcholine, and vesicular loading of glutamate has been shown to enhance acetylcholine content. Using a combination of optogenetics and whole-cell recordings in mice, we now...
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Cholinergic Neurotransmission in Partial Limbic Seizures. Geoffrey Liu, Joshua E. Motelow, Wei Li, Qiong Zhan, Asht M. Mishra, Robert N. S. Sachdev, Abhijeet Gummadavelli, Zaina Zayyad, Hyun Seung Lee, Victoria Chu, John P. Andrews, Dario J. Englot, Peter Herman, Basavaraju G. Sanganahalli, Fahmeed Hyder, Hal Blumenfeld. Partial limbic seizures impair consciousness, but the mechanism of impairm...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2013
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2013.255745